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Taken together these suggest that although GLP1R agonists may increase the risk of pancreatitis and thyroid cancer in rodents, that it has yet to be confirmed in humans

Pregnancy and lactation represent relative contraindications given absence of human safety data in these populations despite reassuring preclinical reproductive toxicology studies

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Same warnings apply to both Both carry warnings around thyroid C-cell tumors (seen in animal studies), pancreatitis, and gallbladder issues, based on their shared hormone-receptor mechanism