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In the SURMOUNT-1 trial (Jastreboff et al., NEJM 2022), adults with obesity (without diabetes) receiving tirzepatide 15 mg weekly achieved a mean weight loss of 20.9% over 72 weeks, compared to 3.1% with placebo
Furthermore, we confirmed GLP-1MK-801-mediated target engagement with NMDA receptors in GLP-1-receptor-positive neurons in the arcuate nucleus using electrophysiological recordings of isolated NMDA receptor currents
Now, let us demonstrate particular results of various studies, which has revealed mechanisms how this peptide can work
[2] [6] According to the product labeling, patients should rotate injection sites with each weekly dose
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