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Instrumentation The oil extraction was done using Borosils SOX012 soxhlet assembly (Figure S8) using petroleum ether (6080 C) as a solvent (Figure S8)
Higher dosage strengths (1.0 mg to 2.4 mg) cost slightly more to compound than microdose formulations because they contain greater amounts of active ingredient per unit volume
In vitro GLP-1 receptor potency measured by cAMP signaling The in vitro potency assay (Novo Nordisk) relied on a reporter gene assay (CRE-luc) and was carried out in baby hamster kidney (BHK-21) cells overexpressing the hGLP-1 receptor
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