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7,8 In one notable case, a patient with no prior psychiatric history developed depressive symptoms and was subsequently treated with sertraline while semaglutide was discontinued, with improvement noted

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Persistent or worsening loss deserves a workup to rule out other drivers

For instance, medications that speed gastric emptying may partially counteract some effects, while those that slow it may intensify side effects

Emphasizing protein-rich foods at each meal enhances satiety and helps preserve lean muscle mass during weight loss, addressing a common concern with rapid weight reduction

This selectivity has been attributed to its specific binding characteristics at the GHSR-1a receptor