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This pushes her effective r factor lower than the female population average of 0.66

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Using these 50 principal components and the top 2000 variable genes, we applied Harmony (18), an algorithm that aligns shared cell types across multiple datasets, to correct batch effects in scRNA-seq data

Since mesenchymal lines typically originate from invasive and metastatic tumors, our results suggest that reduction of SAA metabolism genes and the consequent rewiring of SAA metabolism may represent hallmarks of liver cancer progression

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