Basal and paracetamol-depleted glutathione from human lymphocytes: ethnic variability
Stoyanovsky DA, Jiang J, Murphy MP et al (2014) Design and synthesis of a mitochondria-targeted mimic of glutathione peroxidase, mitoebselen-2, as a radiation mitigator
Genetic Factors: Ethnicity: People with darker skin tones naturally have more melanin, which provides more protection against UV rays
Yet, individuals with pre-existing conditions may be at increased risk of serious adverse effects (including death) if one considers the possibility that large doses of supplemental vitamin E might interfere with medications, and possibly lower their efficacy or increase their toxicity (1)
Drugs Ther
But in inflammatory diseases such as periodontitis, the release of inflammatory mediators, local hypoxia, and activation of immune cells can obviously raise oxidative stress beyond the regulation ability of antioxidant systems, resulting in cellular damage and amplifying inflammation (Albano et al., 2022), (Menzel et al., 2021)