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Although these changes in HR upon GLP-1 RA administration were subtle and the underlying mechanisms are unclear, further studies are necessary to elucidate the long-term effects of GLP-1 RAs primarily on HR and other related variables to clarify whether the elevated HR can be regarded as a transient reflex mechanism or whether it might in fact lead to poor cardiovascular outcomes in a diabetic population

It is not a medicine, not for human or veterinary consumption, and not for any in-vivo administration

What sits beneath it is where the clinical picture becomes more complex

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Centrally injected oxyntomodulin reduces food intake to the same magnitude as GLP-1, despite a much lower receptor affinity (8284)

Clients often report improved focus and endurance