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Published August 2, 2023

Tirzepatide, having received FDA approval, has a more defined safety record, though patients should be monitored for potential risks such as pancreatitis or thyroid tumors, which have been concerns with GLP-1 receptor agonists in general

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and caspase-1, the effector protease that processes IL-1/IL-18 and activates gasdermin D (GSDMD) to induce pyroptosis [91]