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10.1093/gerona/glu057 J Gerontol A Biol Sci Med Sci

Extended follow-up studies are needed to establish the durability of treatment effects and identify any long-term safety concerns that may not be apparent in shorter-term trials

Growth hormone, interferon-, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling

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But it comes with important caveats: lack of FDA approval, variability risks, and transitional regulatory changes

By the point when an individual reaches their forties, this has started to slow to 45 days and persists in slowing as people age