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However, the SOUL trial reported broadly consistent treatment effects for the primary MACE outcome across prespecified subgroups, including CKD-only, CAD-only, and combined CKD/CVD groups (Fig
References 1 AmichJ.DmigM.OKeeffeG.BinderJ.DoyleS.BeilhackA.et al (2016)
It is the first approved dual GIP and GLP-1 receptor agonist, which means it activates two separate incretin pathways that single-agonist medications like semaglutide cannot reach
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