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The trial demonstrated a 20% reduction in the primary composite endpoint of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke (hazard ratio 0.80, 95% CI 0.72-0.90).[1] The trial also demonstrated improvements in multiple cardiovascular biomarkers independent of weight loss
IC 50 , half-maximal inhibitory concentration
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LUPKIN: I'll let Andrea explain it, but the gist is that this SNAC thing creates a little protective buffer zone around the pill to keep it from getting broken down too quickly and help it get absorbed into the bloodstream
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