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Singh, MD, chair of the department of ophthalmology at Mass Eye and Ear in Boston, during his presentation at the Retina World Congress in Fort Lauderdale, Florida

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Landsberg was the first researcher speculating that increased SNS activity in response to weight gain is an adaptive mechanism to increase resting energy expenditure and promote restoration of the antecedent weight (Landsberg, 1986, 2001), while other authors suggested that prolonged sympathetic overactivity might induce weight gain, due to reduced capacity to dissipate excessive calories, mediated by downregulation of adrenoceptors (van Baak, 2001

It begins in skin cells called melanocytes, the cells that produce the color of our skin

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