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Strategy 1: nutritional fortification (the foundation) This is the single most impactful intervention

A combination of resistance and aerobic exercise appears most beneficial for muscle preservation

This suggests that Mounjaro may be superior to Ozempic

4.1 Synthesis of the network meta-analysis Overall, the interventions displayed heterogeneous efficacy, with some compounds producing strong and clinically relevant effects while others contributed only marginal or inconsistent benefits

The cheapest alternatives to semaglutide include older prescription drugs like orlistat and natural supplements like berberine, which are significantly more affordable

Eli Lillys revenues grew by 32% year over year in 2024 as Zepbound and Mounjaro drove volume growth