Pterfi Z, Szilvsy-Szab A, Farkas E, et al
Koren, I
Stack 4: Longevity Sermorelin + MOTS-c + NAD+ The Comprehensive Anti-Aging Protocol For patients focused on slowing biological aging at the cellular level, this three-component stack addresses the major pillars of longevity: growth hormone optimization, mitochondrial function, and cellular repair
CoQ10 is found naturally in our mitochondria, the energy producing organelles of our cells and is essential in the production of cellular energy in the form of adenosine triphosphate (ATP)
After 11 PANCE passages of parallel evolution on GD_SS1.1 and GD_SS1.2, isolated proteases revealed consensus mutations at Asp29Asn, Asn143Asp and Pro174Leu (Extended Data Fig

Protein supplementation combined with resistance training leads to greater preservation of lean mass and strength than training alone. Key point: With adequate protein intake and resistance training, patients can maintainand sometimes increasestrength during GLP-1 therapy despite overall weight loss. Recovery and micronutrients Adequate sleep, hydration, and correction of deficiencies (including vitamin D when present) further support muscle function and recovery. Bottom Line: GLP-1 Medications Improve Body Composition Not Muscle Wasting Semaglutide and tirzepatide do not inherently cause muscle wasting. Most weight lost is fat , and body composition improves. Muscle wasting is primarily a risk of undernutrition , not GLP-1 therapy itself. Protein + resistance training is the most effective strategy to preserve muscle. At Potere Health MD, GLP-1 and GIP therapy is paired with evidence-based nutrition and strength guidance so weight loss is healthier, stronger, and more sustainable