Vraskas Fall Like Prologue to Phyresis, you get some marginal benefit from Vraska's Fall in EDH because your opponents will sacrifice their worst creature to this edict effect, but it'll also give them a poison counter to start proliferating
They are beings who can traverse the multiverse
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Doubling your energy is a huge deal when you have a Commander and dozens of other cards that can generate energy, and turning that energy into huge creature tokens is a great way to take over games
Infect commanders generally revolve around proliferate or poison counters directly, or combat to allow for creatures with infect to attack the opponent directly, oftentimes finding ways around potential blockers
The Flying Crane Technique from earlier is a great example of this in action