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AOD-9604 does not negatively affect insulin sensitivity
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S., Brcic, L., Sever, M., Klicek, R., Radic, B., Drmic, D., Ilic, S., Kolenc, D., Vrcic, H., & Sebecic, B
This small molecule compound demonstrates exceptional ability to block nicotinamide N-methyltransferase enzyme activity, preventing NAD+ depletion while activating sirtuin pathways associated with healthy aging and metabolic optimization
As a defined small molecule, 5-Amino-1MQ is a "tool compound" in the classical pharmacology sense useful for probing NNMT biology specifically
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