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At .30 BAC levels, a person will likely lose consciousness

In a 12-week clinical trial by Leyden et al

These can be signs of an early B12 deficiency or other nutritional deficiencies like folate, vitamin B2 (riboflavin), and vitamin B3 (niacin) deficiency

Both are early enough in development that the published endpoints are surrogates body weight, HbA1c, liver fat measured over trial-length follow-up

J Biol Chem 278:4686946877 Conklin PL, Foyer CH, Hancock RD, Ishikawa T, Smirnoff N (2024) Ascorbate acid metabolism and functions

The proposed protective mechanisms are thought to parallel those implicated in GI infection prophylaxis, primarily by modulating immune function at both local and systemic levels (488)