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C17H30N2O13 / 470
/ IgA1(208-245)-Tn(230) / Immunoglobulin heavy constant alpha 1 (IGHA1)
Two sequential enzymatic reactions are typically required: removal of the 2-O-sulfate by IDS
The installed glycan is O-GlcNAc (GlcNAcβ-O-Ser/Thr)
and mechanism of action studies
AG142000: α-D-GalNAc-Butyl-Carboxylic Acid Pack Size:100 mg C17H30N2O13 / 470C13H23NO8 321. 32 An D N acetylgalactosamine (GalNAc) ligand equipped with a terminal carboxylic acid through a short butyl spacer. The carboxylic acid can be activated to NHS, sulfo NHS, or pentafluorophenyl (PFP) esters and reacted with amine functionalized platforms or lysine residues on proteins and peptides to form stable amide bonds. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the
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