Methotrexate USP Sulfur Compounds (for Synthesis) Test Specification Min Max ABSORPTION

Test Specification Min Max ABSORPTION MAX 514 (395) nm 514 (395) nm RETEST DATE

05 ppm SUITABILITY FOR USE IN DITHIZONE TESTS TO PASS TEST TO PASS TEST WATER 0

3 % EXPIRATION DATE

Pt-Co 15 WATER (w/w) 0

Test Specification Min Max ASSAY (as Ba(OH)2*H[@2@]O) 97

Methotrexate USP Sulfur Compounds (for Synthesis) Test Specification Min Max ABSORPTIONTest Specification Min Max ASSAY (ANHYDROUS BASIS) 98 102. 00% RELATED COMPOUNDS TO PASS TEST ENANTIOMERIC PURITY TO PASS TEST RESIDUE ON IGNITION 0. 10% ELEMENTAL IMPURITIES AS REPORTED AS REPORTED WATER DETERMINATION 12. 00% IDENTIFICATION TO PASS TEST EXPIRATION DATE DATE OF MANUFACTURE APPEARANCE RESIDUAL SOLVENTS TO PASS TEST