Es un medicamento a base de semaglutida que ayuda a controlar la diabetes tipo 2 y tambin a bajar de peso en personas con obesidad y sobrepeso
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Youre moving from a single-receptor medication (GLP-1 only) to a dual-receptor medication (GLP-1 plus GIP), which adds a second hormonal pathway that influences appetite, fat metabolism, and glucose regulation
Neuropharmacology 136:202215 Guo X et al (2023) Tirzepatide ameliorates spatial learning and memory impairment through modulation of aberrant insulin resistance and inflammation response in diabetic rats
For instance, the metabolite hydrogen sulfide (H 2 S), which was produced by Desulfovibrio has been shown to impair GLP-1 expression, thereby disrupting host glucose metabolism (Qi et al., 2024)
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