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Primary endpoint: HF hospitalization or all-cause mortality (up to 52 weeks)
KPV has been characterised in rodent IBD models at micrograms-to-milligrams-per-kilogram oral and intraperitoneal dosing
Some nutrients may help support healthy testosterone levels when deficiencies are present
Cleven AH, Sannaa GA, Briaire-de Bruijn I, Ingram DR, van de Rijn M, Rubin BP, et al
Koikov L, Starner RJ, Swope VB, Upadhyay P, Hashimoto Y, Freeman KT, Knittel JJ, Haskell-Luevano C, Abdel-Malek ZA
Results from a phase 1 trial have supported further clinical evaluation with a dose-dependent WL up to 14.5% with AMG133 compared to 1.5% with placebo by day 85 [59]
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