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Abbreviations NAION: Nonarteritic anterior ischemic optic neuropathy RAPD: Relative afferent pupillary defect ODD: Optic disc drusen GLP-1 RA: Glucagon-like peptide-1 receptor agonist OCT: Optical coherence tomography ETDRS: Early Treatment Diabetic Retinopathy Study BMO: Bruchs membrane opening VA: Visual acuity IOP: Intraocular pressure GCA: Giant cell arteritis SAP: Standard automated perimetry MD: Mean deviation GCL: Ganglion cell layer EDI-OCT: Enhanced depth imaging optical coherence tomography VF: Visual field References Salvetat ML, Pellegrini F, Spadea L, Salati C, Zeppieri M

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They are complementary often studied together as the Wolverine Stack and human evidence for both remains preclinical

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It is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates