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Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinsons disease brains with and without dementia

BCL-2 and glutathione: alterations in cellular redox state that regulate apoptosis sensitivity

The study is expected to last approximately 89 weeks

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The third and smallest part is independent work using retatrutide as a tool compound in rodent models and in isolated tissue: hepatic lipid handling, energy expenditure by indirect calorimetry, food-intake studies with central versus peripheral administration, and a growing set of comparisons against dual and single agonists in the same model