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There is also a class-related warning about thyroid tumors (common to all GLP-1s) based on animal studies, though no such cases were reported in retatrutide trials so far

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Results for anxiety were similar: Are these potential effects on anxiety and depression caused by the weight loss from GLP-1s

Even small changes in how or when you take the medication can affect how well it works

The most commonly reported improvements involve libido, energy, motivation, strength, exercise recovery, and body composition