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The 'Standard' protocol uses a gradual increase in dosage over the first few weeks, while the 'Advanced' protocol suggests a higher initial loading dose for acute injury support, which then tapers down

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Winther KH, Wichman JE, Bonnema SJ, Hegeds L (2017) Insufficient documentation for clinical efficacy of selenium supplementation in chronic autoimmune thyroiditis, based on a systematic review and meta-analysis

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Precision becomes nearly impossible