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This peptide, which he named exendin-4 , was approximately 53% identical in amino acid sequence to human GLP-1, but with one critical difference: while human GLP-1 is degraded by an enzyme called DPP-4 within minutes of being released, exendin-4 was resistant to that breakdown
Pharmacodynamic characteristics of lixisenatide once daily versus liraglutide once daily in patients with type 2 diabetes insufficiently controlled on Metformin
DEG, differentially expressed gene
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GHRH injections in elderly men improved some measures of muscle strength (upright row, shoulder press) but did not consistently improve physical function or IGF-I levels