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Detailed definitions and coding algorithms for all variables are provided in Supplementary Table 1

Furthermore, by clearing the toxic buildup of methylmalonic acid (MMA), B12 helps prevent the incorporation of abnormal fatty acids into cell membranes, thereby protecting the structural integrity of the mitochondria themselves from further metabolic damage

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Upon treatment with 10 mM H 2 O 2 , Prx1 is rendered completely unreactive toward mmPEG 24 (Fig 4H, lane 3), even after subsequent treatment with TCEP, indicative of hyperoxidation of the peroxidatic cysteine

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