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Other adverse effects of hydrocodone include: Respiratory: severe respiratory depression, shortness of breath Cardiovascular: hypotension, bradycardia, peripheral edema Neurologic: Headache, chills, anxiety, sedation, insomnia, dizziness, drowsiness, fatigue Dermatologic: Pruritus, diaphoresis, rash Gastrointestinal: Vomiting, dyspepsia, gastroenteritis, abdominal pain Genitourinary: Urinary tract infection, urinary retention Otic: Tinnitus, sensorineural hearing loss Endocrine: Secondary adrenal insufficiency (17) Hydrocodone acts as an agonist and can cause sedation and respiratory depression when combined with other central nervous system depressants, so patients must not take it with those agents (53)

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Contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, or severe pancreatitis

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Each OTC and prescription option works at a different point in that chain

To check the flow The first time you use each new Ozempic pen be sure to dial to the flow check symbol