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231 Nocturia (waking at night to urinate) can contribute to poor sleep quality and often coexists with chronic insomnia disorder, especially in older individuals

J Nat Med 60(4):303307 Jiang Z, Jin M, Zhou W, Li R, Zhao Y, Jin X, Li G (2018) Anti-inflammatory activity of chemical constituents isolated from the willow bracket medicinal mushroom Phellinus igniarius (Agaricomycetes)

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Since MSM has powerful anti-inflammatory properties, its often used as a natural alternative to medications to improve arthritis-related symptoms