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Patients with diabetic complications, such as retinopathy, autonomic neuropathy, sensorimotor neuropathy, and cardiovascular disease, may require modifications in their exercise regimen

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Imaging and biomarker endpoints The sharpest biomarker lesson from this literature comes from a negative trial

GLP-1s, a class of drugs used to treat type 2 diabetes, obesity, cardiovascular disease, and other conditions, have exploded in popularity in recent years due to their demonstrated effectiveness, but are often not covered by insurance, particularly for the treatment of obesity

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