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and S.O.E
Notably, PPR and Res-NPsalthough both polyphenol-based systemsexert complementary actions: PPR focuses on acute mtROS elimination and mitochondrial stabilization, whereas Res-NPs reinforce endogenous antioxidant defenses through sustained Nrf2 activation
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However, the magnitude of the effect was small
In addition to its role in glucose metabolism, GLP-1 reduces appetite and food intake
Specifically, the drug effectively inhibits the activation of the NF-B signaling pathway, leading to significant reduction in the mRNA expression levels of pro-inflammatory cytokines such as TNF-, IL-6, and IL-1, ultimately delaying the progression of muscle atrophy [29]
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