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Nat Immunol (2014) 15:70716
2,3 These auto-antibodies result in immune complex formation and complement mediated lung injury
TGF- is a major player in myocardial fibrosis by upregulating collagen synthesis and inhibiting collagen degradation, while the production of TGF- is stimulated by high blood glucose levels and insulin resistance which are the main characteristics of diabetes which also promote the manifestation of DCM
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Lower starting doses (200 to 500 mg/day) are typical in younger children
Combining kidney organoids and genome editing Technologies for a Better Understanding of physiopathological mechanisms of renal diseases: state of the art
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