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In addition, transcription factors, such as activating transcription factor 4 (ATF4), nuclear factor erythroid 2-related factor 2 (Nrf2), and p53, can exert antioxidant effects by regulating the GSH/GPX4 pathway (4, 5)
Mice were euthanized following bleeding
Additionally, a decrease in glutathione levels can impair the body's ability to detoxify harmful substances, which can lead to the accumulation of toxins in the body over time
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