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And of course, we think that weight loss is a component, a factor in the benefits that we see
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Farxiga/Forxiga is not currently approved for weight loss as a standalone indication in non-diabetics, but the evidence is accumulating: Currently, if weight loss is the primary goal in a non-diabetic patient, GLP-1 agonists (semaglutide/Ozempic, tirzepatide/Mounjaro) produce substantially greater weight loss (1015% vs 24%)
Similarly, the limited number of records for specific dose of GLP-1 RAs precluded an assessment of dose-response effects
The decision between GLP-1 weight loss injections and bariatric surgery for weight loss is a complex one, depending on individual patient factors, severity of obesity, and desired outcomes
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