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3a) Consistent with a deleterious role for free iron in ASCVD, ApoE-/- mice exposed to chronic iron overload displayed exacerbated atherosclerosis likely secondary to VEC damage or death, which was attenuated by dietary iron restriction or iron chelation 62,63

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doi:10.3390/ijms25084346

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Available from: Accessed on 21/012026 Soliman N, Moisset X, Ferraro MC, et al