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Treatment with FOXO4-DRI at 25 M in serum-limited senescent fibroblast and keloid organ culture models promoted apoptosis, decreased G0/G1 phase cells, and induced p53-pS15 nuclear exclusion confirmed by Annexin V-FITC/PI apoptosis assays and TUNEL staining of keloid organ cultures at days 3, 7, and 10
We apologize to the many colleagues whose fundamental work could not be cited for space constraints
Severe hypoglycemia risk
Because it is gentle and non-invasive, it fits into nearly any treatment plan as a maintenance and support treatment
Several configurations have been developed
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