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Excluded obesity medications for both groups encompassed orlistat, phentermine/topiramate, naltrexone/bupropion, and surgical interventions such as endoscopic sleeve gastroplasty, intragastric balloon placement, adjustable gastric banding, gastric sleeve, and gastric bypass

Acknowledgements The authors are thankful to the animal facility staff (CECEMA, University of Montpellier, France) for their daily assistance, and to Christophe Dorandeu (ICGM) for performing characterization of LNCs

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