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Long-acting GLP-1RAs profoundly suppress glucagoncontinuously, not rhythmically

However, more research is needed to confirm these findings

Moreover, the long-term effects are often best realized when combined with other healthy lifestyle choices, such as a balanced diet and regular exercise

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Search strategy and study selection We conducted a comprehensive systematic search across five electronic databases: PubMed, Embase, Web of Science, Scopus, and the Cochrane Library, as well as the Google Scholar search engine, from inception to September 30, 2025, to identify studies investigating the association between GLP-1 receptor agonists and AUD outcomes