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Women aged 25-45 with BMIs between 25-28 kg/m were randomly assigned to one of two groups: [5] Supresa group: 176.5 mg of standardized saffron extract daily (split into two doses) Placebo group: Identical-looking capsules with no active ingredients A key point that differentiates this study from many weight loss trials is that participants were not placed on any caloric restrictions

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GLP-1R immunoreactivity in glial cells Since earlier publications reported GLP-1R immunoreactivity in glial cells 24,25,26 , we examined potential Glp1r /GLP-1R expression by astrocytes and microglia