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By contrast, first-time prescribing of AOMs increased 21.7% over the same period, from 0.56% to 0.69%

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Since that time, other options have come on the market, including the Eli Lilly drug Zepbound (tirzepatide), which received FDA approval in November 2023

Compounds that chelate free metal ions in a way that prevents them from generating free radicals offer promise in the treatment of neurodegenerative diseases and other chronic diseases in which metal-induced oxidative damage may play a pathogenic role (21)

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