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10.3390/ijms21217977 Int
Compared to other organs, the brain has reduced levels of catalase and glutathione peroxidase activity, impairing its ability to neutralize H 2 O 2 and other electrophilic compounds [175, 176]
4 When considering only NF1-associated, radiation-exposed, and sporadic malignant peripheral nerve sheath tumors, previous studies showed complete loss of H3K27 trimethylation in variable proportions: 29% (12/42), 5 34% (55/162), 10 56% (30/54), 8 57% (51/90), 6 68% (17/25), 9 73% (45/62), 4 and 75% (47/63)
For research procurement, the practical question is whether the documentation is complete enough for the labs internal quality process
Another factor is metabolic compensation
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