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The risk of an immune response is common to peptide drugs in general
and 25 patients received a combination of acetyl-l-carnitine at a dose used in arm A plus low-dose, i.e., 150 mg/day, pregabalin (arm C) for 8 weeks and were subsequently observed for an additional 8 weeks to assess relapse latency and frequency
gingivalis infection upregulates PD-L1 expression on dendritic cells, suppresses CD8+ T-cell responses, and aggravates oral cancer
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Altogether, these examples underscore that despite encouraging experimental results, ferroptosis-targeted drugs face multiple translational bottlenecks, including systemic toxicity, insufficient targeting, metabolic compensation, and biological heterogeneity
Yes, they delay progression to diabetes
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