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A review published in 2025 in the Journal of Crohns and Colitis suggests that GLP-1 medications have both metabolic and anti-inflammatory benefits for people with IBD, with early studies linking them to improved outcomes like fewer hospitalizations
If constipation improves, those were contributing factors
Sleep optimization synergies Sermorelin enhances sleep quality, but foundational sleep hygiene amplifies these benefits
Doses of sitagliptin up to 125 mg/kg (approximately 12 times the human exposure at the maximum recommended human dose) did not impair fertility or harm the fetus
Similarly, a 2024 study published in the Journal of the American Medical Association analyzed data from 16,827 patients and found that those prescribed semaglutide had a significantly higher risk of developing NAION compared to those on non-GLP-1 medications
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