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This author has long recognized the need for a shift of clinical focus from glycemic status to insulin homeostasis for detecting and optimally managing adverse metabolic, proinflammatory, endothelial, developmental, and neurologic effects of hyperinsulinism (ref

Importantly, this approach establishes the conditions needed for structured, connected data environments that support reliable analysis and more advanced analytics

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Label Risk and Category Ambiguity Create Friction The main restraint is credibility

doi: 10.1186/1471-2377-11-62 67 BuchwaldDHerrellRAshtonSBelcourtMSchmalingKSullivanPet al

Journal of Orthopaedic Research , 24(7), 1421-1432.