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Reduced severity of middle ear infection caused by nontypeable Haemophilus influenzae lacking the hemoglobin/hemoglobinhaptoglobin binding proteins (Hgp) in a chinchilla model of otitis media

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Part 2 of this trial included extension over 16 weeks at doses of 2.4 mg, 4.8 mg, and 9.0 mg, resulting in mean weight loss of 4.8%, 8.6%, and 8.3%, respectively, compared to 1.7% for the placebo group (81)