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Pyridoxine (B) in high doses is known to interact with certain drugs: it can reduce the therapeutic efficacy of levodopa by increasing peripheral conversion of levodopa to dopamine (vitamin B speeds up decarboxylation)

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Researchers observed that intra-articular administration was associated with changes in cartilage matrix composition and chondrocyte activity markers in the treated joints compared to controls [3]

It also plays a vital role in neurological function, mood regulation, and metabolism