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This finding contradicts a study in which intravenous Tat treatment in mice led to increased expression of cyclooxygenase-2 (COX-2) and decreased expression of ZO-1 and occludin [188]
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429 Importantly, several mechanisminformed models have now entered clinical validation, guiding trial design for targeted therapies in nonsmall cell lung cancer and other malignancies
Cancer Epidemiology Biomarkers & Prevention
This is a reflection of the efficiency of the conversion of cysteine to sulfate
