In reality, these are unapproved knockoffs that have not been approved as safe and effective and are often made with illicit foreign active pharmaceutical ingredients (API)
Tirzepatide (dual GIP/GLP-1 agonist) typically produces slightly stronger weight loss and maintenance effects than semaglutide alone in clinical trials, maintaining 8590% of results versus semaglutide's 80%+
J Biol Chem 279:16151620 Huang XL, Xu J, Zhang XH, Qiu BY, Peng L, Zhang M, Gan HT (2011) PI3K/Akt signaling pathway is involved in the pathogenesis of ulcerative colitis
More research is needed to determine the SAEs of all GLP-1 drugs
So what do they need to know
Treatment typically involves behavioral therapy, medication or a combination of both to improve focus, emotional regulation and impulse control but some patients taking GLP-1s say theyre experiencing improvements they never achieved with traditional ADHD drugs