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Description

Alzheimer's disease: targeting the cholinergic system

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These doses were used within a controlled research environment with rigorous safety monitoring they do not represent guidance for use outside of trials

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Another bile salts chemosensor is the nuclear farnesoid X receptor (FXR) (347) which activation, contrarily to TGR5, blocks the release of GLP-1 in the colonic L-cells (348), while in the liver induces glycogenesis helping to improve glucose homeostasis

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(IK) Expression levels of SREBP-2 and HMGCR were analyzed using Western blotting, and -actin was used as the loading control

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