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Contrary to expectations, complete lymphadenectomy in these patients did not prolong overall survival, questioning the model of a phased metastatic dissemination from primary site, to regional lymph nodes, to distant sites
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The effect of 2.4 mg once-weekly injected semaglutide in patients with HFpEF, obesity and T2D is currently investigated in an ongoing trial STEP-HFpEF DM (Semaglutide Treatment Effect in People with obesity and HFpEF and type 2 diabetes) (64, 65)